First-generation antihistamines: Relief Now, Problem Tomorrow
First-generation antihistamines, such as diphenhydramine, are used to treat allergies but might cause cognitive impairment due to their anticholinergic properties. A recent study found that continuous use is related with an increased risk of dementia.
Tricyclic antidepressants can cause memory loss.

Tricyclic antidepressants, such as amitriptyline, boost the availability of many neurotransmitters while simultaneously having anticholinergic effects. This raises the risk of dementia and cognitive impairment, particularly in older persons.Continue reading…