Many questions remain about genetics and predisposition, but current evidence shows that heavy, frequent, and long-term use — especially daily use over a year or more — increases risk.
The Three Phases of CHS
Clinicians and researchers describe CHS as progressing through three distinct phases, each with different symptoms:
1. Prodromal Phase
This early stage can last for months or even years before full symptoms appear. It is characterized by:
Persistent or recurring nausea
Mild to moderate abdominal discomfort
Morning queasiness
Occasional fear of vomiting Continue reading…