In CHS, symptoms typically begin within about 24 hours after cannabis use and can continue until the underlying cause is addressed.
People experiencing CHS often report experiencing multiple episodes in a single year, and many have multiple emergency department visits before a correct diagnosis is made.
Why Does CHS Happen?
Although researchers are still investigating the exact cause, CHS appears to result from the chronic overstimulation of the body’s endocannabinoid system, which plays an important role in regulating nausea, digestion, and the body’s stress responses.
Cannabis contains compounds called cannabinoids — particularly THC (delta-9-tetrahydrocannabinol) — that interact with cannabinoid receptors in both the brain and the gastrointestinal tract. Continue reading…